Trade Name: FLOXAPEN CAPSULE 250 MG
Generic Name: Flucloxacillin

Presentation
Each capsule contains 250 mg Flucloxacillin Sodium BP.
Dry powder in amber glass bottle for reconstitution into 100ml syrup. After reconstitution each 5 ml contains 125 mg of Flucloxacillin as Flucloxacillin sodium BP.

Mode of action
Peptidoglycan is the building block of bacterial cell wall. Flucloxacillin inhibits the synthesis of peptidoglycan by blocking Peptidoglycan Synthetase enzyme. So bacterial cell wall formation is inhibited. Without cell wall bacteria can not survive.

Uses
It is indicated for the treatment of infections due to Gram-positive organism, including infections caused by Beta Lactamase- Producing staphylococci. Typical indications include.

Skin and soft tissue infections
Boils, Abscesses, Carbuncles. Infected skin conditions, e.g. ulcer, eczema, and acene. Furunculosis, cellulitis, infected wounds, Infected burns protection for skin grafts. Otitis media and extern, impetigo.

Respiratory tract infections
Pneumonia, Lung abscess, Empyema, Sinusitis, Pharyngitis, Tonsillitis, Quinsy.

Other infections caused by Flucloxacillin-sensitive organisms
Osteomyelitis, Enteritis, Endocarditis, Urinary tract infection. Meningitis, septicemia. It is also indicated for use as a prophylactic agent during major surgical procedures where appropriate; for example, cardiothoracic and orthopedic surgery.

Dosage and Administration
Usual adult dosage (including elderly patients) :
2 tsp q.i.d. The dosage may be doubled where necessary; Oral doses should be administered ½-1 hour before meals. Osteomyelitisl endocarditis-Upto 8 gm daily, in divided doses six to eight hourly.

Packaging Quantities
Floxapen 500 : Box containing 4x5's capsules in alu-alu foil.
Floxapen 250 : Box containing 5x10's capsules.
Floxapen D/S : 100 ml Bottle
Floxapen P/D : 15 ml Bottle