Trade Name: FENOLID CAPSULE 200 MG
Generic Name:
Fenofibrate BP
Presentation:
Fenolid Capsule: Each capsule contains
Fenofibrate BP 200 mg.
Indications:
Fenofibrate is used in treatment
of hyperlipidaemias of IIa, IIb, III, IV and V in patients who have not
responded adequately to diet and other appropriate measures.
Dosage and
administration:
Initially 1 capsule daily (dose
form not appropriate for children or in renal impairment).
Precautions:
Renal impairment; liver function
tests recommended every 3 months for first year
(discontinue treatment if significantly raised).
Side effects:
Gastrointestinal (e.g. nausea,
anorexia, gastric pain), pruritus, urticaria, impotence; also headache,
dizziness, vertigo, fatigue, hair loss, rash, photosensitivity, raised serum
transaminases, hepatitis. Also reported anemia, leucopenia, thrombocytopenia.
Contraindications:
Severe renal or hepatic
impairment, existing gall bladder disease.
Drug
interactions:
Fenofibrate potentiates the
action of oral anticoagulants. In patients receiving oral anticoagulants
therapy, the dose should be reduced by one third on starting fenofibrate and
then adjusted.
Fenofibrate should not be used in
combination with perhexiline maleate or with monoamino oxidase inhibitors (MAOIs).
Fenofibrate has been given in
combination with statins in resistant hyperlipidemias but the incidence of
muscle problems and rhabdomyolysis is increased and care must be exercised.
In pregnancy
and lactation:
Fenofibrate should not be given
in pregnancy and breast-feeding.
Pharmaceutical precautions:
Store in a dry place below 250C
and protect from light. Keep out reach of children.
Commercial
Pack:
Each box contains 10 blister
strips of 4 capsules.
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