Trade Name: GALFIN CAPSULE 150 MG
Generic Name:
Fluconazole INN
Presentaion
Galfin 50:
Each capsule contains
Fluconazole INN 50 mg.
Galfin 150:
Each capsule contains
Fluconazole INN 150 mg.
Indications
Galfin
is indicated in the treatment of acute or recurrent Vaginal candidiasis, Mucosal
candidiasis (Oropharyngeal candidiasis, Oesophagitis, Candiduria), Systemic
candidiasis (including Candidemia, Disseminated candidiasis), Cryptococcal
infections (including Meningitis), Tinea pedis, Tinea corporis, Tinea cruris,
Pityriasis versicolor, Dermal candidiasis.
Dosage and administration
Vaginalcandidiasis: A single
dose of 150 mg.
Mucosal candidiasis: 50 mg
daily (100 mg daily in unusually difficult infections) given for 7-14 days in
Oropharyngeal candidiasis; for 14-30 days in other Mucosal infections (e.g.
Oesophagitis, Candiduria).
Systemic candidiasis and
Cryptococcal infections: 400 mg initially then 200 mg daily, increased if
necessary to 400 mg daily. Treatment continued according to response.
Tinea pedis, Tinea corporis,
Tinea cruris, Pityriasis versicolor, Dermal candidiasis: 50 mg daily for 2-4
weeks (for up to 6 weeks in Tinea pedis).
Child over 1 year: Superficial
Candidal infections, 1-2 mg/kg daily; Systemic candidiasis and Cryptococcal
infections, 3-6 mg/kg daily (in serious life threatening infections up to 12
mg/kg daily has been given to children aged 5-13 years-max 400 mg daily).
Contraindications
Fluconazole is contraindicated to patients hypersensitive to this drug and in
advanced liver disease.
Cautions
Caution should be taken in
renal impairment, pregnancy, breast-feeding and hepatic disease.
Side effects
Fluconazole is generally
well tolerated. Some side effects are nausea, abdominal discomfort, diarrhoea,
flatulence, headache, rash. Less frequently hepatic disorders, angioedema,
anaplylaxis reported.
Drug Interactions
Rifampicin decreases plasma
levels of Fluconazole. Fluconazole increases the effect of warfarin,
benzodiazepines and phenytoin. It increases the plasma concentration of
sulphonylureas, theophylline.
Pregnacy and lactation
Fluconazole should be used
in pregnancy only when the benefit claearly outweighs the risk. Fluconazole
should be avoided during lactation.
Commercial Pack
Glfin 50: Each box
contains 3 blister strips of 10 capsules.
Glfin 150: Each box contains 3 blister strips of 10 capsules.
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