Trade Name: EPICLON TABLET 0.5 MG
Generic Name: Clonazepam USP

Presentation:

Epiclon 2: Each tablet contains Clonazepam USP 2.0 mg. 
Epiclon 0.5: Each tablet contains Clonazepam USP 0.5 mg 

Indications:

Panic Disorder, Epilepsy, Status epilpticus , Lennox Gastaut Syndrome, Infantile spasm, Absences , Tonic-clonic sezures , Myoclonic seizures , Myoclonic seizures, Myoclonic seizures , Partial seizures , Drug induced dyskinesisa, Choreiform movements , Fulgurant pain, Bipolar affective disorder, 

Dosage and administration:

Panic disorder: 
Adults: initial dose The recommended initial dosage of clonazepam is 0.25 mg twice daily. increment dose-0.5-1 mg at interval of 3 days. To reducte the inconvenience of somnolence, administration of one dose at bedtime may be desirable, 
Pediatric patients: There is no clinical trail experience with clonazepam in panic disorder patients under 18 years of age.
Seizure disorder: 
Adult: initial dose -1 mg daily in divided dose (elderly 0.5 mg) Not to exceed 1.5 mg/day. Increased to 1-3 mg. 5-12 years: 0.5 mg increased to 3-6 mg, 

Contraindications: Clonazepam must not be used in patients with ---

-- known hypersensitivity to benzodiazepines, 
-- acute pulmonary insufficiency and 
-- respiratory depression, 

Precautions : The dosage of Clonazepam must be carefully adjusted to individual requirements in elderly patients, patients with preexisting  disease of the respiratory system (chronic obstructive pulmonary disease) liver or kidneys and in patients undergoing treatment with other centrally action medications or anticonvulsant agents. Like all drugs of this type, Clonazepam may, depending on dosage, administration, and individual susceptibility, modify the patient's reactions (driving ability, behavior in traffic). Clonazepam should be withdrawn slowly and abrupt discontinuance of the d\rug should be avoided, especially during ling-term, high-dose therapy to avoid precipitating seizures, status epilepticus, or withdrawal symptoms, 

Pregnancy, nursing mother : No controlled trails have been carried out so far in pregnant women, Under these circumstances , the drug should only be administered to pregnant women if the potential benefits outweigh the risk to the fetus. Clonazepam passes into the breast milk; it must not be taken during breast - feeding. If there is a compelling indication for Clonazepam, breast- feeding should be discontinued.

Side effects: It has no toxic effect on the organs, even when given for long periods. The following undesirable effects occur relatively frequently; fatigue, drowsiness, muscular hypotonia, dizziness, light-headedness and ataxia. These effects are usually transient and generally disappear spontaneously i9n the course of the treatment or on reduction of the dosage, They can be partially prevented by increasing the dose slowly at the start at the start of treatment. 

Drug Interactions:  Concurrent administrations of hepatic enzyme inducers such as carbanazepine, phenobarbitone or phenytoin, may accelerate the metabolism of Clonazepam, Concomitant intake of alcohol may effect the patient's response to Clonazepam. Clonazepam may be expected to have the sedative interaction associated with benzodiazepines in general. 

Commercial Pack: 
Epiclon 2 : Each box contains 3 blister strips of 10 tablets 
Epiclon 0.5: Each box contains 4 blister strips of 10 tablets