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Management of Diarrhoea in Children

Professor Md. Salim Shakur
PhD. (DU), FRCPCH (UK), FRCP (London), FRCP (Edin), FRCP (Glasgow)
MRCP (UK), DCH (Glasgow), DCH (Dublin) MBBS (Dhaka)
Director & Senior Colsultant Dhaka Shishu (Children) Hospital & Academic Director (Ex.)
Bangladesh Institute of Child Health

IINTRODUCTION

The term "Diarrhoea" derives from Greek word; literally meaning Òthrough followingÓ. It is a common digestive disorder that virtually all people suffer at some stages during their lives. Diarrhoea is one of the principal causes of morbidity & mortality among children in the developing world. In 1982, on the basis of a review of active surveillance data from global studies conducted in the 1950s, 1960s and 1970s, it was estimated that 4.6 million children died annually from Diarrhoea.
 

DEFINITION

The definition of Diarrhoea varies but it can generally be taken to mean increased stool water causing an increase in stool frequency or the passage of soft stools greater than 3 times per day or presence of blood in stool even once a day is also called Diarrhoea (Bloody Diarrhoea or invasive Diarrhoea). Diarrhoea is called acute if it lasts for less than two weeks or persistant having acute onset if it lasts for greater than two weeks.

HISTORY

It is difficult to find out when first case of Diarrhoea was found. History of cholera is treated as the history of Diarrhoea. In the past, people traveling in ships would hang a yellow flag if one or more of the crew members suffered from cholera. Boats with a yellow flag hung would not be allowed to disembark at any harbor for an extended period, typically 30 to 40 days. Cholera was originally endemic to the Indian subcontinent, with the Ganges River likely serving as a contamination reservoir. The disease spread by trade routes (land and sea) to Russia, then to Western Europe, and from Europe to North America.
 

EPIDEMIOLOGY
Diarrhoeal disease is one of the leading causes of morbidity and mortality in the least developed countries, especially among children aged 0-5 years (Fewtrell et. al 2005). Global estimates of the numbers of deaths due to Diarrhoea have shown a steady decline, from 4.6 million in the 1980s (Snyder and Merson 1982) to 3.3 million in the 1990s (Bern et al. 1992) to 2.5 million in the year 2000 (Kosek, Bern, and Guerrent 2003), 1.5 million in 2004. However, diarrhoeal diseases



continue to be an important cause of morbidity and mortality worldwide and despite all advances in health technology, improved management, and increased use of oral rehydration therapy (ORT) in the past decades, they remain among the five major killers of children under five years of age. In contrast to mortality trends, morbidity due to Diarrhoea has not shown a parallel decline, and global estimates remain between two and three episodes of Diarrhoea per child under five per year.

1816-1826 : First Cholera pandemic:                        The pandemic began in                         Bengal, and then spread                         across India by 1820.

1829-1851 : Second Cholera                        pandemic reached                        Europe, London and                        Paris in 1832

1961-1970s : Seventh Cholera                          pandemic began in                          Indonesia, called El Tor                          after the strain, and                          reached Bangladesh in                          1963
 
1816-1826 : First Cholera pandemic:                        The pandemic began in                         Bengal, and then spread                         across India by 1820.

1829-1851 : Second Cholera                        pandemic reached                        Europe, London and                        Paris in 1832

1961-1970s : Seventh Cholera                          pandemic began in                          Indonesia, called El Tor                          after the strain, and                          reached Bangladesh in                          1963
 
1816-1826 : First Cholera pandemic:                        The pandemic began in                         Bengal, and then spread                         across India by 1820.

1829-1851 : Second Cholera                        pandemic reached                        Europe, London and                        Paris in 1832

1961-1970s : Seventh Cholera                          pandemic began in                          Indonesia, called El Tor                          after the strain, and                          reached Bangladesh in                          1963
 
1816-1826 : First Cholera pandemic:                        The pandemic began in                         Bengal, and then spread                         across India by 1820.

1829-1851 : Second Cholera                        pandemic reached                        Europe, London and                        Paris in 1832

1961-1970s : Seventh Cholera                          pandemic began in                          Indonesia, called El Tor                          after the strain, and                          reached Bangladesh in                          1963