PRESCRIBING INFORMATION
Presentation
Elocan Ointment: Each gram ointment contains Mometasone Furoate USP 1 mg.

Pharmacodynamic Properties
Like other corticosteroids, Mometasone Furoate has anti-inflammatory, antipruritic and vesoconstrictive properties. The mechanism of the anti-inflammatory activity of topical steroids, in general, is unclear. However corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is release from the membrane phospholipids by phospholipase A2.

Indications
Elocan ointment is a medium potency corticosteroid indicated for
* Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
* It may be used in paediatric patients 2 years of age or older

Dosage and Application
Apply a thin film of Elocan ointment to the affected skin areas once daily.

Paediatric use
Elocan ointment can be used with caution in paediatric patients 2 years of age or older. The safety and efficacy of this drug use for longer than 3 weeks have not been established. Safety and efficacy of Elocan ointment is not established in paediatric patients below 2 years.

Contraindications
Elocan ointment is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.

Side Effects
Burning, itching, irritation, dryness, or redness of the skin may occur when this medication is first applied to the skin. These effects should disappear in a few days as your body adjusts to the medication.

Precautions
Elocan ointment is for external use only. If irritation develops, Elocan should be discontinued and appropriate therapy instituted. After applied this ointment, never cover the skin with an airtight bandage, a tight diaper, plastic pants, or any other airtight dressing.

Drug Interaction
No information provided.

Use in Pregnancy and Lactation
Pregnancy category C. There are no adequate and well-controlled study on teratogenic effects from topically applied corticosteroids in pregnant woman. Therefore, topical corticosteroids should used during pregnancy only if the potential benefit justified the potential risk to the fetas.
It is not known whether topical administration of corticosteroid could result in sufficient systemic absorption to produce detectible quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Elocan ointment is applied to a nursing mother.

Overdose
Topically applied Elocan ointment can be absorbed in sufficient amounts to produce systemic effects.

Storage Condition
Store in a cool and dry place. Keep away from light and out of reach of children

Commercial Pack
Elocan Ointment: Each pack has an aluminium collapsible tube containing 5 gm of ointment.